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Tuesday, February 5, 2019

Beneficial effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes.

PMID:  Diabetes Metab. 2016 Sep ;42(4):234-41. Epub 2016 May 18. PMID: 27209439 Abstract Title:  Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: A randomized, double-blind, placebo-controlled trial. Abstract:  BACKGROUND: To our knowledge, data on the effects of probiotic supplementation on glycaemic control and lipid concentrations in patients with gestational diabetes mellitus (GDM) are scarce.AIM: The aim of the present study was to determine the effects of probiotic supplementation on glycaemic control and lipid profiles in GDM patients.METHODS: Sixty pregnant women with GDM, primigravida and aged 18-40years, were divided into two groups to receive either probiotic capsules (n=30) or a matching placebo (n=30) in this randomized double-blind, placebo-controlled trial. The patients in the probiotic group took a daily capsule that contained three viable freeze-dried strains: Lactobacillus acidophilus (2×10(9)CFU/g), L. casei (2×10(9)CFU/g) and Bifidobacterium bifidum (2×10(9)CFU/g) for 6weeks. The placebo group took capsules filled with cellulose for the same time period. Fasting blood samples were taken at the beginning and end of the study to quantify the relevant markers.RESULTS: After 6weeks of intervention, probiotic supplementation vs a placebo resulted in significant decreases in fasting plasma glucose (-9.2±9.2mg/dL vs +1.1±12.2mg/dL, P

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from GreenMedInfo http://bit.ly/2MNoSJe

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