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Wednesday, February 6, 2019

Probiotic supplementation improves inflammatory status in patients with rheumatoid arthritis.

PMID:  Nutrition. 2014 Apr ;30(4):430-5. Epub 2013 Dec 17. PMID: 24355439 Abstract Title:  Probiotic supplementation improves inflammatory status in patients with rheumatoid arthritis. Abstract:  OBJECTIVES: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease in which the gut microbiota is altered. Probiotics are microorganisms that can normalize gut microbiota; thus, they may help to alleviate RA symptoms. The objective of the present clinical trial was to assess the effects of probiotic supplementation on disease activity and inflammatory cytokines in patients with RA.METHODS: Forty-six patients with RA were assigned into two groups in this randomized, double-blind, placebo-controlled clinical trial. The patients in the probiotic group received a daily capsule that contained a minimum of 10(8) colony-forming units of Lactobacillus casei 01 for 8 wk. The placebo group took capsules filled with maltodextrin for the same time period. Questionnaires, anthropometric measurements, and fasting blood samples were collected, and the participants were assessed by a rheumatologist at baseline and at the end of the trial.RESULTS: Disease activity score was significantly decreased by the intervention, and there was a significant difference between the two groups at the end of the study (P

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from GreenMedInfo http://bit.ly/2SxPOlF

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